LCT – Living Cell Technologies

Thought i might add this to the discussion on LCT.

nice to see the churn happening; Merrill describes this churn as a shift from value to growth investors. A lot of happy punters from lower prices will be tempted to sell or free carry here and they are being bought into by growth investors who are looking beyond at the potential for this company.

As for Biotech, it can be a dangerous game because there is so much bullsh*t out there.

I’ve been burnt before – I thought I had a good thing at MBP post obesity trial disaster before it tanked again.

Thats why I make my next investment foray into biotech very cautiously. So why is LCT a better bio to invest in, and not a dud?

1. Proven patient base – Type 1 diabetics and insulin dependent Type 2 diabetics (uncontrolled by triple therapy [i.e. metformin/glitazones/sulphonylureas]).

Note: 10-15% of all diabetics are Type I IDDM (Insulin dependent Diabetes Mellitus).

Diabetes is the worlds fastest growing chronic disease in Australia and the world.

2. Easy to monitor outcomes – BGL monitoring is simple and accurate.

3. Physiology –

(A) bodies need insulin to control glucose levels, driving blood glucose into the liver into storage form (glycogen) and cells

(B) If you can replace the insulin you have cure. Currently as type 1 diabetics know, you need to inject insulin everyday – and depending on your requirements this can be once daily or two to three times daily. Insulin comes in many forms fast acting (i.e. ActRapid)/short acting/longacting i.e. Lantus/Lemevir.

C) Porcine Insulin is a proven product. In fact many insulin analogues are already porcine variant, so we use it already and it has been proven safe over millions of patients over many years.

D) So what are Living Cell doing? They are implanting porcine cells to take over the job the human cells were doing previously, but are now unable to do. (Many reasons – wikipedia it :p)

Proven market. Proven physiology.

Proven Product.

And apparently – working well on the patients they’ve implanted so far. It’s lovely to see proper human trials – as much as I love lab rats I’d rather see results in fellow beings =)

So what are the trials for?


These products pass through 4 phases where safety is evaluated in larger and larger clinical groups before the product is let out onto the public.